If you’ve ever wished your comfort food could work harder for your goals, this high protein lasagna bake is exactly what you need. We’re talking serious layers, real flavor, and enough protein to power you through the busiest day. In this article, I’ll walk you through how to make this dish step-by-step. We’ll cover the ingredients that boost protein without compromising taste, tips for baking it just right, and even how to meal prep it for the week. You’ll also find a protein breakdown and answers to the most common questions. Let’s start where all great recipes do, with a story from my kitchen.
Table of Contents
The Story Behind My Favorite High Protein Lasagna Bake
Why I Created This High Protein Lasagna Bake
I still remember the first time I tried to make lasagna on my own. I’d just moved into my first apartment, my pantry was bare, and all I had was a box of noodles, some ground turkey, and cottage cheese. I knew I needed something filling that wouldn’t wreck my macros. So I layered it all together, crossed my fingers, and hoped for the best. What came out wasn’t pretty, but it was surprisingly good. That version sparked something. Over the years, I refined it—more flavor, more protein, less fat, and more balance. Now, this high protein lasagna bake is one of my go-to comfort meals. It’s hearty and cheesy, but with a macro-friendly twist that fits perfectly into a fitness-focused lifestyle.
Why This Recipe Just Works
There’s something so satisfying about digging into a warm slice of lasagna. But traditional recipes are often heavy and low in protein. This one flips the script. We use lean ground turkey, part-skim cheeses, and a layer of cottage cheese for extra protein. The pasta stays in because it adds texture and satisfaction. It’s not about cutting everything out. It’s about building smart, crave-worthy meals that support your goals without feeling like a sacrifice. Whether you’re meal prepping or feeding a hungry crew, this high protein lasagna bake is a guaranteed crowd-pleaser.
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High Protein Lasagna Bake That Actually Tastes Amazing
- Total Time: 50
- Yield: 8 servings 1x
Description
This high protein lasagna bake is layered with lean ground turkey, cottage cheese, and part-skim cheeses for a comforting, macro-friendly meal. Great for dinner or meal prep.
Ingredients
9 lasagna noodles, cooked
1 lb 93% lean ground turkey
2 cups marinara sauce
1 cup low-fat cottage cheese
1/2 cup part-skim ricotta cheese
1 1/2 cups shredded part-skim mozzarella
1/4 cup grated parmesan
1 tsp garlic powder
1 tsp Italian seasoning
Salt and pepper to taste
Instructions
1. Preheat oven to 375°F.
2. Cook lasagna noodles according to package. Set aside.
3. In a skillet, brown ground turkey. Season and add marinara sauce. Simmer 5 minutes.
4. Mix cottage cheese and ricotta in a bowl. Add salt.
5. In a 9×13 dish, layer meat sauce, noodles, cheese mixture, and mozzarella. Repeat layers.
6. Top with remaining sauce and mozzarella. Sprinkle parmesan.
7. Cover with foil and bake 25 minutes. Uncover and bake 10 more until golden.
8. Let rest 10 minutes before slicing.
Notes
Store leftovers in fridge for 4 days or freeze for 2 months.
Use no-boil noodles to save time. Make ahead and refrigerate overnight.
- Prep Time: 15
- Cook Time: 35
- Category: High-protein recipes
- Method: Baking
- Cuisine: American, Italian-inspired
Nutrition
- Serving Size: 1 slice
- Calories: 420
- Sugar: 5g
- Sodium: 620mg
- Fat: 13g
- Saturated Fat: 6g
- Unsaturated Fat: 7g
- Trans Fat: 0g
- Carbohydrates: 28g
- Fiber: 3g
- Protein: 37g
- Cholesterol: 55mg
High Protein Lasagna Bake Ingredients and Macros
Simple, High Protein Ingredients That Make a Difference
What makes this high protein lasagna bake stand out is its balance of lean meat, high-protein dairy, and strategic layering. Every ingredient pulls its weight to give you flavor and macros in one pan. Instead of traditional beef, we go with 93% lean ground turkey. It’s flavorful but significantly lower in fat, which lets us keep calories in check without losing richness. For the cheeses, part-skim mozzarella and cottage cheese bring that creamy, cheesy texture while packing extra protein. A little grated parmesan on top adds that golden, savory finish that makes this dish feel like comfort food in every bite.
Whole wheat lasagna noodles offer more fiber than white pasta, which helps with digestion and keeps you full longer. They’re sturdy enough to hold the layers together but light enough to complement the cheese and sauce. Speaking of sauce, choose one with no added sugar and at least 3 grams of protein per serving. Some store brands are surprisingly macro-friendly if you check the label. If you’re in a rush, jarred marinara works. If you’re cooking on the weekend, simmer your own with crushed tomatoes and garlic.
Nutritional Breakdown per Serving
This recipe makes 8 hearty portions. Each serving of this high protein lasagna bake delivers about 37 grams of protein, 28 grams of carbs, and 13 grams of fat. The total calorie count per serving lands around 420 calories, making it a strong choice for both cutting and maintaining muscle. You’ll get a nice spread of macros that fuel energy, support recovery, and satisfy hunger.
Nutrient Breakdown:
Nutrient | Per Serving |
---|---|
Protein | 37 g |
Carbohydrates | 28 g |
Fat | 13 g |
Calories | 420 |
This balance makes it a flexible recipe whether you’re fueling up after the gym or prepping lunch for the week.

How to Make the Best High Protein Lasagna Bake
Step-by-Step Cooking Instructions
Making this high protein lasagna bake is easier than you’d think. Start by preheating your oven to 375°F. While it warms up, boil a pot of water and cook your lasagna noodles according to the package instructions. Drain them and lay them flat on a baking sheet so they don’t stick together.
Next, cook your protein. In a skillet over medium heat, brown one pound of lean ground turkey. Season it with salt, pepper, garlic powder, and Italian herbs. Once it’s fully cooked, stir in about 2 cups of marinara sauce and let it simmer for 5 minutes. This builds flavor and keeps the meat juicy.
In a separate bowl, mix together one cup of low-fat cottage cheese, half a cup of part-skim ricotta, and a pinch of salt. This will be your creamy protein layer.
Now comes the fun part, assembling. In a 9×13 inch baking dish, start with a thin layer of meat sauce. Lay down three noodles, then spread half of the cheese mixture over them. Sprinkle some shredded part-skim mozzarella. Repeat the layers until you’ve used everything, ending with sauce and cheese on top. Sprinkle with grated parmesan for extra flavor.
Cover the dish with foil and bake for 25 minutes. Remove the foil and bake another 10 minutes until bubbly and golden. Let it rest for 10 minutes before slicing so everything holds together perfectly.
Time-Saving Tips for Busy Days
If you’re short on time, you can use no-boil noodles to skip a step or assemble the entire bake the night before. Store it covered in the fridge, then pop it in the oven when you get home. You can even divide it into two smaller pans and freeze one for later. Just thaw overnight in the fridge and bake as usual.
This high protein lasagna bake is also meal-prep friendly. Cut it into eight squares, store in airtight containers, and refrigerate for up to four days. It reheats beautifully in the microwave or oven.
FAQ
How much protein is in baked lasagna?
Traditional lasagna tends to fall on the lower end of the protein scale, offering between 12 and 18 grams per serving depending on the ingredients. But this high protein lasagna bake packs a punch. Each portion delivers around 37 grams of protein, thanks to the combination of lean turkey, cottage cheese, ricotta, and mozzarella. It’s a major upgrade for anyone tracking macros or aiming to build or maintain muscle.
What’s the best way to store leftovers?
Let the lasagna cool completely, then cut it into portions. Store each slice in an airtight container in the fridge for up to four days. If you want to freeze it, wrap each slice tightly or use freezer-safe containers. It will stay fresh for up to two months. Reheat in the microwave or oven until warmed through.
Can I use different protein sources?
Absolutely. Ground chicken, lean beef, or even plant-based crumbles can work well here. The key is choosing a protein source that’s lean, flavorful, and holds its texture when baked. You can also blend in chopped spinach or zucchini for extra nutrients without affecting the flavor.
How do I keep it from getting watery?
Use low-moisture cheeses and let the meat sauce simmer before layering. After baking, rest the dish for 10 minutes before slicing. That time allows everything to set and keeps the lasagna firm, not soggy.
This high protein lasagna bake is more than just another healthy twist on a classic. It’s comfort food you can feel good about, packed with flavor and fuel that fits your fitness goals. Whether you’re feeding a crowd, meal prepping for the week, or just craving a warm and satisfying dinner, this recipe is designed to deliver. You don’t have to give up your favorite dishes. You just need to build them smarter. This one hits all the right notes. And yes, you can absolutely have seconds.